Frumkin I*, Vassallo C* & Laub M.

de novo genes that provide specific and general phage defense in E. coli

submitted, 2024

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Frumkin I and Laub M.

Selection of a de novo gene that can promote survival of E. coli by modulating protein homeostasis pathways

Nature Ecology and Evolution, 2023

​  -- News & Views - Nature Ecology and Evolution, November 2023

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Aharon-Hefetz N, Frumkin I, Mayshar Y, Dahan O, Pilpel Y, Rak R.

Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest

eLife, 2020

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Frumkin I #, Yofe I, Bar-Ziv R, Gurvich Y, Lu Y, Voichek Y, Schirman D, Krebber H & Pilpel P #

Evolution of intron splicing towards optimized gene expression is based on various cis and trans molecular mechanisms

PLOS Biology, 2019

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Frumkin I, Lajoie JM, Gregg JC, Hornung G, Church MG & Pilpel Y

Codon usage of highly expressed genes affects proteome-wide translation efficiency

PNAS, 2018

 

Frumkin I*, Schirman D*, Rotman A*, Li F, Zahavi L, Mordret E, Asraf O, Wu S, Levy S & Pilpel Y

Gene architectures that minimize cost of gene expression

Molecular Cell, 2017

​  -- Preview - Cell Systems, January 2017

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Bar-Yaacov D, Frumkin I, Yashiro Y, Chujo T, Chemla Y, Blumberg A, Orr Schlesinger, Bieri P, Greber B, Ban N, Zarivach R, Alfonta L, Pilpel Y, Suzuki T and Mishmar D

Mitochondrial 16S rRNA is methylated by tRNA methyltransferase TRMT61B in all vertebrates

PLoS Biology, 2016

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Yona AH, Frumkin I & Pilpel Y

A relay race on the evolutionary adaptation spectrum

Cell, 2015

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Avci D, Fuchs S, Schrul B, Fukumori A, Breker M, Frumkin I, Chen CY, Schilling O, Steiner H, Schuldiner M & Lemberg MK

The yeast ER protease Ypf1 refines nutrient sensing by regulating transporter abundance

Molecular Cell, 2014

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Yona AH*, Bloom-Ackerman Z*, Frumkin I*, Hanson-Smith V, Charpak-Amikam Y, Feng Q, Boeke JD, Dahan O & Pilpel Y

tRNA genes rapidly change in evolution to meet novel translational demands

eLife, 2013

  -- Research Highlight - Nature Reviews Genetics, January 2014

  -- Podcast - eLife, December 2013

  -- Faculty of 1000 Recommended

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Krumpe K*, Frumkin I*, Herzig Y, Rimon N, Özbalci C, Brugger B, Rapaport D & Schuldiner M

Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

Molecular Biology of the Cell, 2012

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